Metastases that result in a net loss of bone are termed osteolytic, while those associated with excessive bone formation are categorised as osteoblastic. It is important to note that both bone degradation and deposition likely occur early in the metastatic process.4
The highest risk of MBD is within the first three to five years after the initial diagnosis, before the cancer reaches a stable state (eg no increase or decrease in severity or extent). However, bony metastasis can present as late...
