In 2020, 1.4 million men were diagnosed with PCa, resulting in 375 000 deaths. In South Africa, PCa accounts for 13% of morbidity among men diagnosed with cancer. The incidence of PCa is projected to increase to 2.9 million cases by 2040, driven by changing age structures (older people account for an increased proportion of the population) and improving life expectancy.^2,3

Risk factors

PCa risk varies significantly with age, genetics, lifestyle, and other health conditions. Older men (>79-years) have a...