The prevalence of BPH increases with age, affecting 50%-60% of men in their 60s and 80%-90% of men >70-years. BPH is rare in men <40-years but is more common in those with a family history of the condition, obesity, and metabolic syndrome.1
BPH is diagnosed histologically by the proliferation of smooth muscle, epithelium, and stromal cells in the prostate's transition zone, which surrounds the proximal urethra.2
Symptoms result from two mechanisms:2
- Static: Hyperplastic tissue compresses the urethra.
- Dynamic: Increased...
